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目的观察中西医结合分期治疗小儿哮喘临床疗效。方法将120例小儿哮喘分为治疗组60例和对照组60例,对照组采用常规西医治疗方案,治疗组除重度患者结合西药外,其余患者均服用中药治疗。急性期观察治疗前及治疗2周后临床症状与体征改变,缓解期观察治疗1年期间肺功能指标和生命质量量表评分的变化,并评价临床疗效。结果治疗组在改善急性发作期喘息、胸闷和哮鸣音方面优于对照组(P<0.05)。两组治疗后肺功能差异无统计学意义(P>0.05)。治疗后3个月、6个月、1年3个时间段,治疗组哮喘患儿的生命质量评分低于对照组(P<0.05)。结论中西医结合疗法比单纯西医治疗哮喘急性发作期能更有效地改善哮喘患儿的症状和体征;哮喘非急性发作期,服中药可提高哮喘患儿生命质量。
Objective To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of pediatric asthma. Methods 120 cases of pediatric asthma were divided into treatment group (60 cases) and control group (60 cases). The control group was treated with conventional western medicine. The patients in the treatment group were treated with traditional Chinese medicine except severe western medicine. The changes of clinical symptoms and signs before and after 2 weeks of treatment were observed in acute phase. The changes of pulmonary function and quality of life scores during 1 year of remission were observed and the clinical efficacy was evaluated. Results The treatment group was better than the control group in improving wheezing, chest tightness and wheezing in acute attack (P <0.05). There was no significant difference in pulmonary function between the two groups after treatment (P> 0.05). After 3 months, 6 months and 1 year after treatment, the quality of life of asthmatic children in the treatment group was lower than that of the control group (P <0.05). Conclusion Integrative Medicine can improve the symptoms and signs of asthmatic children more effectively than Western medicine in the treatment of acute exacerbation of asthma. In the non-acute exacerbation of asthma, taking traditional Chinese medicine can improve the quality of life of asthmatic children.