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细胞角蛋白在肝细胞和胆管细胞的不同表型与细胞功能密切相关。通过胚胎肝组织发生过程中角蛋白表型的变化和肿瘤性肝细胞不同成份角蛋白表达的异质性研究,提示成年人肝脏可能贮备有多潜能干细胞。此外,细胞角蛋白作为细胞系标记物,其病理学的改变是肝脏疾病的参考指标。
The different phenotypes of cytokeratins in hepatocytes and cholangiocytes are closely related to cell function. Heterogeneity of keratin phenotypes and keratin expression of different components of tumor hepatocytes during embryonic liver tissue development suggest that adult adult liver may have pluripotent stem cells. In addition, cytokeratin as a cell line marker, the pathological changes of liver disease is a reference index.