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三、抗过敏介质剂:变态反应的病理炎症变化主要是由过敏介质或生物活性淋巴因子引起的,如组织胺、5—羟色胺、缓激肽和慢反应物质等。这些活性介质能引起平滑肌痉挛、毛细血管通透性增加、炎症细胞渗出、组织的坏死和增生等,因而发生炎症反应和病理损伤,形成各种变态反应性疾病。由于这些活性物质作用的部位和强度不同,其所导致的病变性质和临床表现也就不同,如作用于皮肤,则引起荨麻疹;作用于呼吸道,则出现支气管哮喘;作用于血管,则
Third, anti-allergic agents: allergic pathological inflammatory changes are mainly caused by allergic media or biologically active lymphokines, such as histamine, serotonin, bradykinin and slow reaction substances. These active mediators can cause smooth muscle spasm, increased capillary permeability, inflammatory cell exudation, tissue necrosis and hyperplasia, etc., and thus cause inflammatory reactions and pathological injuries, forming a variety of allergic diseases. Due to the different sites and strengths of these active substances, the nature of the lesions and their clinical manifestations are different. If they act on the skin, they cause urticaria; when they act on the respiratory tract, bronchial asthma occurs; on the blood vessels,