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研究报道单功能树状高分子(dendrimers)可通过自我封接寡核苷酸桥链形成具有多功能的树状高分子群,这意味着如果需要传输A药到含有X受体的细胞,只需将具有靶向该受体分子的树状高分子与载药树状高分子连接起来即可。将药物与人工聚合物相连的多聚物治疗策略可能实现药物的靶向?
It has been reported that monofunctional dendrimers form a multifunctional dendritic polymer population by self-sealing oligonucleotide bridges, which means that if it is necessary to deliver A drug to X receptor-containing cells It is only necessary to connect the dendrimer having the target molecule to the drug-carrying dendrimer. Is it possible to target drugs by multi-drug treatment strategies that link drugs to artificial polymers?