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目的探讨美托洛尔对慢性充血性心力衰竭患者血B型钠尿肽水平的影响。方法选择我院2008年2月至2010年2月慢性充血性心力衰竭患者83例,将以上患者随机分为两组,观察组和对照组。其中对照组采用常规治疗,观察组在对照组治疗基础上给予美托洛尔治疗。治疗前后测定两组患者血浆血浆B型钠尿肽水平。结果观察组治疗后B型钠尿肽水平与对照组治疗后比较,差异有统计学意义(P<0.05);两组患者总有效率比较,差异有统计学意义(P<0.05)。结论在常规治疗基础上应用美托洛尔能够显著改善慢性充血性心力衰竭患者临床症状,改善血浆B型钠尿肽水平,临床效果显著,值得临床借鉴。
Objective To investigate the effects of metoprolol on blood B-type natriuretic peptide in patients with chronic congestive heart failure. Methods Eighty-three patients with chronic congestive heart failure from February 2008 to February 2010 in our hospital were randomly divided into two groups: observation group and control group. Among them, the control group received routine treatment, while the observation group received metoprolol treatment on the basis of the control group. Plasma B-type natriuretic peptide levels were measured in two groups before and after treatment. Results After treatment, the level of B-type natriuretic peptide in the observation group was significantly lower than that in the control group (P <0.05). The total effective rate of the two groups was statistically significant (P <0.05). Conclusion The application of metoprolol on the basis of routine treatment can significantly improve the clinical symptoms and improve the level of plasma B-type natriuretic peptide in patients with chronic congestive heart failure. The clinical effect is significant and is worthy of clinical reference.