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选取我院收治的糖尿病肾病患者84例,随机分为观察组和对照组各42例。在糖尿病肾病诊疗常规的基础上,对照组加用缬沙坦胶囊口服,观察组采用缬沙坦联合雷公藤多甙口服治疗。对比两组患者治疗前后24小时尿蛋白定量、血肌酐的变化情况结果:两组患者治疗后的血肌酐水平均显著低于治疗前(均P<0.05),观察组治疗后的24小时尿蛋白定量为(1.31±0.81)g,显著低于治疗前和对照组治疗后(均P<0.05)。结论:缬沙坦联合雷公藤多甙能有效降低糖尿病肾病患者的蛋白尿,改善患者的肾功能。
84 cases of diabetic nephropathy admitted to our hospital were randomly divided into observation group and control group, 42 cases each. On the basis of routine diagnosis and treatment of diabetic nephropathy, valsartan capsules were orally administered in the control group and valsartan combined with tripterygium glycosides in the observation group. The changes of urinary protein and serum creatinine in 24 hours before and after treatment were compared between the two groups. Results: The serum creatinine levels in both groups were significantly lower than those before treatment (all P <0.05). After 24 hours of treatment, urinary protein The quantification was (1.31 ± 0.81) g, which was significantly lower than that before treatment and control group (all P <0.05). Conclusion: Valsartan combined with Tripterygium glycosides can effectively reduce proteinuria in patients with diabetic nephropathy and improve renal function in patients.