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目的:探讨水囊联合米索前列醇用于足月妊娠引产的效果和安全性。方法:选取本院妇产科2011年1月-12月有引产指征的产妇96例,将其随机分为观察组与对照组,每组48例。观察组采用水囊联合米索前列醇阴道后穹窿给药,每次25ug,间隔4小时重复使用,对照组采用静脉滴注催产素方式,对比观察两组产妇的引产效果和安全性。结果:观察组与对照组的引产成功率分别为93.8%、79.2%,差异具有显著性(P<0.01)。结论:在足月妊娠引产中应用水囊联合米索前列醇阴道后穹窿给药,具有较为理想的效果与安全性,值得进一步推广。
Objective: To investigate the efficacy and safety of water balloon combined with misoprostol for induction of term labor. Methods: A total of 96 maternal women with induced labor were selected from January to December 2011 in our hospital. They were randomly divided into observation group and control group with 48 cases in each group. The observation group was treated with water sac combined with misoprostol vaginal fornix, each time 25ug, repeated every 4 hours. The control group was given intravenous drip oxytocin. The induction and safety of two groups were observed. Results: The success rates of induction of labor in observation group and control group were 93.8% and 79.2% respectively, the difference was significant (P <0.01). Conclusion: The application of water sac combined with misoprostol vaginal fornix in full-term pregnancy induced labor has the ideal effect and safety, which is worth further promotion.