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目的:观察无创通气治疗老年慢性阻塞性肺疾病(COPD)合并Ⅱ型呼吸衰竭的临床疗效。方法:对36例老年COPD合并Ⅱ型呼吸衰竭患者在常规对症治疗的基础上采用双水平正压无创通气(BiPAP)呼吸机辅助通气治疗,观察治疗前及治疗后2h、6h和24h血气分析变化并进行比较。结果:无创通气治疗后2～6h动脉血氧分压(PaO2)、动脉血二氧化碳分压(PaCO2)和动脉血氧饱和度(SaO2)升高,pH改善,呼吸频率(RR)和心率(HR)减慢,24h内呼吸衰竭基本纠正,各项指标与治疗前比较,差异有显著性(P<0.01)。结论:无创通气治疗老年COPD合并Ⅱ型呼吸衰竭可明显改善患者的临床症状、纠正缺氧和CO2潴留,尽早应用能阻止病情恶化,适合临床广泛应用。
Objective: To observe the clinical efficacy of noninvasive ventilation in the treatment of senile chronic obstructive pulmonary disease (COPD) with type Ⅱ respiratory failure. Methods: Thirty-six elderly COPD patients with type 2 respiratory failure were treated with BiPAP ventilator-assisted ventilation on the basis of routine symptomatic treatment. The changes of blood gas analysis before and 2h, 6h and 24h after treatment were observed And compare. Results: PaO2, PaCO2 and SaO2 increased, pH improved, respiratory rate (RR) and heart rate (HR) increased from 2 to 6 h after non-invasive ventilation ) Slowed down within 24h respiratory failure basic correction, the indicators compared with before treatment, the difference was significant (P <0.01). Conclusion: Noninvasive ventilation in elderly patients with COPD and type Ⅱ respiratory failure can significantly improve the clinical symptoms of patients, correct hypoxia and CO2 retention, as soon as possible to prevent the deterioration of the application, suitable for clinical application.