论文部分内容阅读
当血管壁受损伤后,血小板在损伤部位与胶原、内皮下微纤维接触,以粘附、释放和聚集等一系列功能参与止血、凝血过程(附图)。如上述某一功能发生缺陷,则会导致出血,称为血小板功能缺陷性疾病。本病并不少见,据国内外文献报道占出血性疾病的60～70%。其临床主要表现为粘膜和皮肤轻至中度出血,此外可伴有消化道、泌尿道出血及手术或创伤后伤口出血不止,女性并可有月经过多。关于血小板功能缺陷性疾病的临床分类,各家的意见不一,多数分为遗传性和获得性两大类。Hardisty将遗传性这一类又分为对胶原、血管内皮下组织粘附功能的缺陷、释
When the vascular wall is damaged, platelets contact the collagen and subendothelial microfibrils at the site of injury, and participate in the hemostasis and coagulation processes with a series of functions such as adhesion, release and aggregation (with photos). If one of the above functions is defective, it can cause bleeding, called a platelet-deficient disease. The disease is not uncommon, according to domestic and foreign literature accounted for 60 to 70% of hemorrhagic disease. The main clinical manifestations of mucous membrane and skin mild to moderate bleeding, in addition may be associated with gastrointestinal, urinary tract bleeding and bleeding wounds after surgery or trauma, women may have menorrhagia. On the clinical classification of platelet dysfunction disease, different opinions, the majority is divided into two major categories of genetic and acquired. Hardisty this hereditary is divided into collagen, endothelium tissue adhesion defects, release