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本文报告30例新生儿肺透明膜病尸检病例,其中9例肺组织作了电镜观察,并讨论发病病因。新生儿肺透明膜病(Hyaline membrane disease)又称新生儿呼吸窘迫综合征(IRDS),多见于早产儿及低体重儿,临床表现为出生后不久出现进行性呼吸困难、紫绀和呼吸衰竭等。病理以肺泡壁及细支气管壁附着嗜伊红性透明膜和肺不张为特征。我室于1982～1986年在106例新生儿尸检中有新生儿肺透明膜病30例(28.3%),居死因首位。我们将此30例尸检资料整理分析,并对其中9例肺组织作了电镜观察。
This article reports 30 cases of neonatal hyaline membrane disease autopsy, including 9 cases of lung tissue under electron microscopy, and discuss the etiology. Hyaline membrane disease, also known as neonatal respiratory distress syndrome (IRDS), is more common in preterm and low birth weight infants. Clinical manifestations include progressive dyspnea, cyanosis and respiratory failure shortly after birth. Pathology with the alveolar wall and the bronchial wall attached eosinophilic transparent film and atelectasis is characterized. In our hospital from 1982 to 1986, there were 30 cases (28.3%) of neonatal hyaline membrane disease in 106 neonates autopsy, ranking the first place in the cause of death. We analyzed the autopsy data of 30 cases and observed the electron microscopy of 9 cases of lung tissue.