论文部分内容阅读
目的探讨老年高血压并缺血性卒中患者同型半胱氨酸(Hcy)的表达及临床意义。方法选取2012年3月至2014年5月老年高血压并发缺血性卒中患者48例为卒中组,其中首次发病28例,复发20例,另选同期单纯老年高血压患者48例为非卒中组,对所有患者血清Hcy及相关指标进行测定。结果卒中组患者Hcy水平高于非卒中组,维生素B12与叶酸水平低于非卒中组(P<0.05);卒中患者中,复发者Hcy水平高于首次发病者,维生素B12与叶酸水平低于首次发病者(P<0.05)。结论对于老年高血压患者,其Hcy表达与缺血性卒中相关,监测Hcy对高血压患者缺血性卒中的预防与治疗具有重要意义。
Objective To investigate the expression and clinical significance of homocysteine (Hcy) in elderly patients with hypertension and ischemic stroke. Methods From March 2012 to May 2014, 48 elderly patients with hypertension complicated by ischemic stroke were selected as the stroke group, of which 28 were the first and 20 were relapsed, and 48 were selected as the non-stroke group , All patients serum Hcy and related indicators were measured. Results The level of Hcy in stroke patients was higher than that in nonstroke patients and the levels of vitamin B12 and folic acid were lower than those in nonstroke patients (P <0.05). The levels of Hcy in relapsed patients were higher than those in first stroke patients and the levels of vitamin B12 and folic acid were lower than those in first stroke patients The incidence (P <0.05). Conclusion The expression of Hcy is associated with ischemic stroke in elderly hypertensive patients. Monitoring Hcy is of great importance in the prevention and treatment of ischemic stroke in hypertensive patients.