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目的 观察 1 60例老年性肺气肿病人及 70例正常老年人肺循环和外周血内皮素的变化情况。方法 采用 X线、心脏 B超、心电图检查心脏情况 ,采用放免法检测外周血内皮素的含量。结果 老年性肺气肿组有右心系统病理损害者 60例 (38.0 %) ,而正常老年人组仅 4例 (5.7%) (P<0 .0 0 1 ) ;老年性肺气肿组外周血内皮素的含量显著高于正常老年人组 (P<0 .0 0 1 )。结论 老年性肺气肿对肺循环产生重要影响 ,可使心血管系统产生病理性损害。
Objective To observe the changes of pulmonary circulation and peripheral blood endothelin in 160 elderly patients with emphysema and 70 normal controls. Methods X-ray, heart B ultrasound, ECG examination of the heart, using radioimmunoassay detection of peripheral blood endothelin content. Results There were 60 cases (38.0%) of pathological damage of right heart in elderly patients with emphysema, compared with 4 cases (5.7%) in normal elderly group (P <0.01) The content of endothelin was significantly higher than that of the normal group (P <0.01). Conclusion Senile emphysema has an important effect on pulmonary circulation, which can cause pathological damage to the cardiovascular system.