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目的了解高原地区婴幼儿分离的耐甲氧西林金黄色葡萄球菌(MRSA)临床分布特点及其耐药性,为儿科临床合理选用抗菌药物提供参考。方法回顾性分析某院2008-2011年住院婴幼儿分离的社区获得性MRSA(CAMRSA)资料。结论 329株CA-MRSA分离自此期间住院婴幼儿的血液、脓汁、痰液等。所有菌株均对万古霉素、利奈唑胺敏感。结论婴幼儿社区获得性MRSA感染中,CA-MRSA的分离率占63.5%,故儿科临床医生应加强对CA-MRSA的监测,重视抗生素的合理使用。
Objective To understand the clinical distribution and drug resistance of methicillin-resistant Staphylococcus aureus isolated from infants and young children in the plateau area, and to provide a reference for rational selection of antibacterials in pediatrics. Methods A retrospective analysis of community-acquired MRSA (CAMRSA) data from hospitalized infants and young children in a hospital from 2008 to 2011 was performed. Conclusions 329 strains of CA-MRSA were isolated from blood, pus and sputum of infants and young children hospitalized during this period. All strains were sensitive to vancomycin and linezolid. Conclusion The prevalence of CA-MRSA in infants with community-acquired MRSA infection is 63.5%. Therefore, pediatric clinicians should strengthen the monitoring of CA-MRSA and pay attention to the rational use of antibiotics.