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本文对国产多孔面钛合金植入物骨长入生物固定进行了实验观察。植入柱形假体(多孔面孔径200～600 μm,孔隙率44％)于成年家兔股骨下端。设骨水泥对照组,实验组在12周内分组观察。荧光、偏光显微镜和电子探针微区分析等切片观察表明,假体植入两周后多孔内就有骨组织长入,8～12周多孔内被骨充盈。力学测试表明,多孔面假体植入后两周即可达到与骨水泥相当的剪切固定强度,但产生一定的抗张固定强度则需要4～6周时间;多孔面骨界面具有与骨质相似的力学特性,有利于应力传递。结果证实国产钛合金多孔面骨长入生物固定在假体固定中的可行性。
In this paper, domestic porous titanium alloy implant bone ingrowth biological fixation experiments were observed. Implantation of cylindrical prosthesis (200 ~ 600 μm pore size, porosity 44%) at the lower end of adult rabbit femur. Set bone cement control group, the experimental group within 12 weeks grouped observation. Fluorescence, polarized light microscopy and electron probe microanalysis and other sections of the observation showed that two weeks after implantation of the prosthesis in the porous bone there is ingrowth, 8 to 12 weeks porous within the bone filling. Mechanical tests show that the perforated prosthesis reaches the shear strength equivalent to bone cement two weeks after implantation, but it takes 4 to 6 weeks to produce a certain tensile strength. Similar mechanical properties are conducive to stress transfer. The results confirm the feasibility of biomedical fixation of porous titanium plate made in China.