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本文应用经皮穿刺附睾吸精子（ｐｅｒｃｕｔａｎｅｏｕｓｅｐｉｄｉｄｙｍａｌｓｐｅｒｍａｓｐｉｒａｔｉｏｎ，ＰＥＳＡ）经卵细胞浆内显微注射技术（ｉｎｔｒａｃｙｔｏｐｌａｓｍｉｃｓｐｅｒｍｉｎｊｅｃｔｉｏｎ，ＩＣＳＩ），对因精道不通致不育的８对夫妇进行治疗。按ＩＶＦ常规促超排卵方案及阴道Ｂ超取卵，共８个周期。ＰＥＳＡ有３例为输精管绝育术后吻合失败者，５例为先天双侧输精管缺如（ＣＢＡＶＤ），吸出精子活率１～８０％，精子密度２～８２×１０６／ｍｌ，共获６９个成熟卵母细胞，ＩＣＳＩ后７个卵子损伤，６２个存活，其中可见２原核正常受精的５０个，正常受精率为８０．６４％，至１９９８年８月已有５例妊娠，临床妊娠率为６２．５％，出生１例健康男婴，发育正常。结果显示，ＰＥＳＡ结合ＩＣＳＩ技术治疗精道不通不育，是一种有效的治疗方法。
In this study, 8 couples with infertility due to impotence were treated with percutaneuspididymalspermaspiration (PESA) via intracytoplasmic microsurgical injection (ICSI). According to IVF convention to promote ovulation program and vaginal B-oocyte retrieval, a total of 8 cycles. There were 3 cases of PESA with unsuccessful anastomosis after vasectomy, 5 cases of congenital bilateral vas deferens absence (CBAVD), aspiration of sperm motility 1 ~ 80%, sperm density 2 ~ 82 × 106 / ml, a total of 69 mature Oocytes, 7 eggs were injured after ICSI, 62 survived, of which 2 were prokaryotic normal fertilized 50, the normal fertilization rate was 80.64%, to August 1998 5 cases of pregnancy, the clinical pregnancy rate was 62 .5%, 1 healthy boy was born, normal development. The results show that PESA combined with ICSI technology is impotent impotence, is an effective treatment.