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Proteins that are modified by a small ubiquitin to form ubiquitin chains are dedicated to proteasomes for degradation.Most of proteins undergo complete degradation,while a small group of proteins are degraded partially by proteasomes to form truncated functional products.Recently,researchers from Chinese Academy of Sciences reveal that Ter94/p97 ATPase and K11-linked ubiquitin chains play an important role in partial proteasomal degradation.
Proteins that are modified by a small ubiquitin to form ubiquitin chains are dedicated to proteasomes for degradation. Most of proteins undergo complete degradation, while a small group of proteins are degraded partially by proteasomes to form truncated functional products. Published, researchers from Chinese Academy of Sciences Sciences reveal that Ter94 / p97 ATPase and K11-linked ubiquitin chains play an important role in partial proteasomal degradation.