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目的探究对剖宫产后人工流产患者联合使用米前列醇和丙泊酚药物进行手术的效果。方法首先将患者随机分为Ⅰ、Ⅱ、Ⅲ三组,第Ⅰ组患者于术前不进行任何处理,第Ⅱ组术前使用米索前列醇药物,第Ⅲ组术前使用米索前列醇药物,手术过程中静脉推注丙泊酚。结果第Ⅱ组和Ⅲ组患者的宫颈松弛程度明显比第Ⅰ组患者要大(P<0.05),三组患者之间的人流综合症的发生率和出血量差异较小(P>0.05),三组患者的疼痛程度差异较大(P<0.05),其中第Ⅲ组患者均无痛感,第Ⅱ组多数患者有轻微痛感,第Ⅰ组绝大多数患者有明显痛感,三组患者发生头晕和乏力不良症状的差异较小(P>0.05),第Ⅰ组患者发生呕吐的比例为31%,明显高于第Ⅱ组(17%)和第Ⅲ组(8%),差异较大(P<0.05)。结论为剖宫产后人工流产患者联合使用米前列醇和丙泊酚药物进行手术的效果较好。
Objective To investigate the effect of combined use of mifepristone and propofol on induced abortion after cesarean section. Methods The patients were randomly divided into three groups Ⅰ, Ⅱ and Ⅲ. The patients in group Ⅰ were treated without preoperatively. The patients in group Ⅱ were treated with misoprostol preoperatively. The patients in group Ⅲ were treated with misoprostol Intravenous infusion of propofol during surgery. Results The degree of cervical relaxation in group Ⅱ and group Ⅲ was significantly higher than that in group Ⅰ (P <0.05). There was no significant difference between the three groups in the incidence and amount of bleeding syndrome (P> 0.05) There were significant differences in the degree of pain between the three groups (P <0.05), among which the patients in group Ⅲ had no pain, the patients in group Ⅱ had mild pain, the patients in group Ⅰ had obvious pain, the patients in group Ⅲ had dizziness and (P> 0.05). The incidence of vomiting in group I was 31%, which was significantly higher than that in group II (17%) and group III (8%) (P < 0.05). Conclusion The effect of combined use of mifepristone and propofol for surgical induced abortion after cesarean delivery is better.