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自体静脉移植被广泛应用于治疗动脉闭塞性疾病 ,但血管内膜增生及粥样硬化导致的再狭窄严重影响了远期疗效。已有资料[1,2 ] 证明 ,平滑肌细胞 (ＳＭＣ)过度增殖与移行是导致内膜增生的主要因素。而血管紧张素转换酶抑制剂 (Ａ ＣＥＩ)对血管ＳＭＣ增殖有抑制作用[3 ] 。我们通
Autologous vein graft is widely used in the treatment of arterial occlusive disease, but the restenosis caused by intimal hyperplasia and atherosclerosis seriously affects the long-term efficacy. It has been reported [1,2] that the over proliferation and migration of smooth muscle cells (SMCs) are the main factors leading to intimal hyperplasia. Angiotensin-converting enzyme inhibitors (A CEI) inhibit the proliferation of vascular SMC [3]. We pass