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应用放射受体分析法研究发现６１５系小鼠外周血淋巴细胞（ＰＢＬ）具有对高密度脂蛋白（ＨＤＬ３）特异、高亲和性、可饱和的ＨＤＬ受体。Ｌ６１５小鼠白血病淋巴细胞ＨＤＬ受体活性明显增高，其受体最大结合量（Ｂｍａｘ）明显高于正常对照组（Ｐ＜０．００１），亲和力虽较正常降低，但随外周血白细胞数升高，亲和力则逐渐增高［Ｋｄ值分别为（４．５３３±０．４１）×１０－８ｍｏｌ／Ｌ（Ｐ＜０．００１）、（３．６５±０．２７）×１０－８ｍｏｌ／Ｌ、（３．００±０．１４）×１０－８ｍｏｌ／Ｌ，Ｐ＞０．０５］，直至与正常对照组无明显差异。而Ｂｍａｘ却逐渐降低，分别为５．６５±０．２４μｇ／ｍｇ细胞蛋白、４．４０±０．２３μｇ／ｍｇ细胞蛋白、３．３２±０．９３μｇ／ｍｇ细胞蛋白（Ｐ＜０．００１）。
Radioimmunoassay study found that 615 line mouse peripheral blood lymphocytes (PBL) with high-density lipoprotein (HDL3) HDL3 specific, high affinity, saturated HDL receptor. L615 mouse leukemia lymphocyte HDL receptor activity was significantly increased, the maximum receptor binding (Bmax) was significantly higher than the normal control group (P <0.001), while the affinity was lower than normal, but with the number of peripheral white blood cells increased (Kd) were (4.533 ± 0.41) × 10-8mol / L (P <0.001), (3.65 ± 0.27) × 10-8mol / L, respectively 3.00 ± 0.14) × 10-8mol / L, P> 0.05], until no significant difference with the normal control group. While Bmax decreased gradually (5.65 ± 0.24μg / mg cell protein, 4.40 ± 0.23μg / mg cell protein and 3.32 ± 0.93μg / mg cell protein respectively (P <0.001) .