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Fukushima和Tooyoshima曾报道一些氨基酸衍生物对实验动物肿瘤有一定的治疗作用.我所在对抗菌素及微生物的代谢产物筛选过程中,发现氧代赖氨酸对小鼠多种实体瘤有效。鉴于此化合物有一定的理论和实际意义,本文扼要介绍它在动物试验中的研究结果。 氧代赖氨酸系由我所抗菌素室从我国辽宁省大连地区土壤中分离得到的新种玫瑰录褐链霉菌(Streptomyces roseoviridofuscus,n.sp.)所产生的抗菌素。它是一种抗代谢类碱性氨基酸,为水溶性白色针状结晶,其游离碱分子式为C_5H_(12)N_2O_3,结构式为
Fukushima and Tooyoshima have reported that some amino acid derivatives have a therapeutic effect on experimental animal tumors.During the screening of metabolites of mycotoxins and microorganisms, my research found that oxotyrosine is effective in a variety of solid tumors in mice. In view of this compound has some theoretical and practical significance, this article briefly introduces its research results in animal experiments. Oxylysine is an antibiotic produced by a new breed of Rose Streptomyces roseoviridofuscus (n.sp.) Isolated from soil in our country’s Liaoning province in our country. It is an anti-metabolic class of basic amino acids, water-soluble white needle-like crystals, the free base formula C_5H_ (12) N_2O_3, the structural formula