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目的探讨泮托拉唑与奥美拉唑治疗急性脑血管疾病并发应激性溃疡出血患者的临床疗效。方法选取2013年8月至2015年8月辽宁省核工业总医院收治的125例急性脑血管疾病患者作为研究对象,按随机数字表法将其分为甲组(60例)和乙组(65例)。两组患者均采用常规疗法治疗脑血管疾病,同时甲组患者给予泮托拉唑,乙组患者采用奥美拉唑进行治疗,比较两组患者的临床疗效及不良反应发生情况。结果甲组患者治疗的总有效率明显高于乙组,差异有统计学意义(χ2=21.584,P<0.05);两组患者的不良反应发生率差异无统计学意义(P>0.05)。结论在急性脑血管疾病并发应激性溃疡出血患者的临床治疗中,泮托拉唑的效果更佳,其能迅速止血,改善病情,且用药安全性高。
Objective To investigate the clinical efficacy of pantoprazole and omeprazole in the treatment of acute cerebrovascular disease complicated with stress ulcer hemorrhage. Methods A total of 125 patients with acute cerebrovascular disease who were admitted to Liaoning Nuclear Industry General Hospital from August 2013 to August 2015 were selected as research objects and divided into two groups according to the random number table method: Group A (60 cases) and Group B example). Both groups were treated with conventional therapy for cerebrovascular disease. Patients in group A were treated with pantoprazole. Patients in group B were treated with omeprazole. The clinical efficacy and adverse reactions were compared between the two groups. Results The total effective rate of treatment in group A was significantly higher than that in group B, the difference was statistically significant (χ2 = 21.584, P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusions Pantoprazole is more effective in the treatment of patients with acute cerebrovascular disease complicated with ulcer due to stress ulcer. It can stop bleeding quickly and improve the condition, and the medication is safe.