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目的探讨脑出血患者急性期周围血白细胞计数与临床之间的关系。方法脑出血患者入院后24小时内采指尖血做白细胞计数,观察不同出血量、出血部位、病情危重度和死亡患者的白细胞增高率。结果白细胞增高组病死率高于白细胞正常组,脑叶出血白细胞增高率低于其他部位出血(P<0.05),基底节大面积脑出血白细胞增高率高于其他部位(P<0.05),50 ml以上出血患者白细胞增高率显著增加(P<0.01)。结论脑出血急性期周围血白细胞增高提示病情重、死亡率高,可作为预后判断的临床指标之一。
Objective To investigate the relationship between peripheral blood leukocyte count and clinical stage in patients with intracerebral hemorrhage. Methods Cerebral hemorrhage was collected within 24 hours after admission. Finger blood samples were collected for white blood cell count. The rates of leukocytosis in different bleeding volume, bleeding site, critical illness and death were observed. Results The mortality in leukocytosis group was higher than that in normal leukocyte group. The leukocytosis rate in lobar hemorrhage was lower than that in other sites (P <0.05), and the increase rate of large area hemorrhage in basal ganglia was higher than that in other sites (P <0.05) The leukocytosis rate in the above bleeding patients increased significantly (P <0.01). Conclusions The increase of peripheral leukocytes in the acute stage of ICH suggests that the disease is heavy and the mortality rate is high, which may be used as one of the clinical indicators for prognosis judgment.