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作者对瑞典南部Helsingborg城进行了癌症的发生与接触氧化铁粉尘关系的流行病学调查。该城有一个用黄铁矿(FeS_2)生产硫酸的工厂,自1905年开始生产以来接触高浓度(约为50～100毫克/米~3)的氧化铁粉尘,其中砷含量为0.01～0.1％。调查方法:从该城1958—1971年间国家癌症登记册里找出肺、胃、肝、肾和膀胱癌及恶性血液病的病例;又从该城市人口登记册里为每个病例选出同年度的,在性别(男性)、年龄(±2.5岁之内)和居住条件(同一地段或邻近的地段)上配对的两例对照。再从该工厂的档案里核查选出的病例和对照有无氧化铁粉尘的接触史。自癌症诊断之日起,
The authors conducted an epidemiological investigation of the association between cancer incidence and iron oxide dust in Helsingborg City, southern Sweden. The city has a factory that produces sulfuric acid from pyrite (FeS 2) and has been exposed to high levels of iron oxide dust (about 50-100 mg / m 3) since 1905, with arsenic levels of 0.01-0.1% . Method of investigation: cases of lung, stomach, liver, kidney and bladder cancer and hematologic malignancies were identified from the National Register of Cancer of the city between 1958 and 1971; and the same year for each case was also selected from the city population register The two controls were paired on the basis of gender (male), age (± 2.5 years) and living conditions (same lot or adjacent lots). From the file of the factory, the selected cases and the history of exposure to iron oxide dust were checked. Since the date of diagnosis of cancer,