胃幽门螺杆菌感染与胃癌:胃癌低发和高发区胃镜调查对照

• 作 者: 李瑜元 林汉良 赵世明
• 机 构: 广州市第一人民医院,中山医科大学附属第一医院,兰州军区总医院 广州510180
• 出 处: 临床消化病杂志
• 发表日期: 1996年04期
• 关键词: 胃镜检查 胃幽门螺杆菌 尿素酶法 活检组织学 肠上皮化生 癌前病变 尿素酶试验 粘膜萎缩 消化性溃疡 内镜表现

我们在胃癌低发区广州和高发区兰州市各选一间医院.对同月接受胃镜检查的全部病人进行活检组织学、幽门螺杆菌(HP)尿素酶法检测.结果显示兰州市胃癌和胃溃疡检出率高,该地区慢性胃炎病人HP感染率高,感染年龄提前,胃炎的组织学模式也有特点,即胃炎多犯及全胃,胃粘膜萎缩发生率高.本研究显示HP早年感染和胃癌相关,但还有多种其他因素促进胃癌形成.

We selected one hospital each in Guangzhou, a low incidence area of ​​gastric cancer, and Lanzhou, a high incidence area. We performed biopsy and Helicobacter pylori (HP) urease assay on all patients who underwent gastroscopy in the same month. The results showed that Lanzhou City has gastric cancer and gastric ulcer. The detection rate is high, the HP infection rate of patients with chronic gastritis in this area is high, the age of infection is advanced, and the histological pattern of gastritis is also characterized, namely gastritis and more gastroenteritis, gastric mucosa atrophy incidence is high. This study shows that HP early infection and gastric cancer Related, but there are many other factors that promote the formation of gastric cancer.