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胃粘膜肠化是胃粘膜良恶性病变的一种常见的伴随病变。此病变与胃癌的关系,迄今尚无定论。多数作者认为不完全大肠型肠化与胃癌的发生关系密切。但肠化是否为胃癌的癌前病变,意见尚不统一。因此,正确认识各类肠化对研究胃癌的组织发生和早期发现很有意义。 1 肠化的概念胃粘膜肠化是指胃粘膜上皮被肠型上皮所代替。此病变首先由Küffer于1988年所描述。根据北医病理教研室4225例胃粘膜活检病例分析,慢性萎缩性胃炎肠化检出率最高(60％),
Gastric intestinal metaplasia is a common concomitant lesion of benign and malignant lesions of the gastric mucosa. The relationship between this disease and gastric cancer has so far been inconclusive. Most authors believe that incomplete colorectal intestinal metastasis is closely related to the occurrence of gastric cancer. However, whether intestinal metaplasia is a precancerous lesion of gastric cancer is not uniform. Therefore, it is of great significance to correctly understand various types of intestinal metastasis for studying the histogenesis and early detection of gastric cancer. 1 The concept of intestinal metaplasia Gastric intestinal metaplasia means that gastric epithelium is replaced by intestinal epithelium. This lesion was first described by Küffer in 1988. According to the analysis of 4225 cases of gastric mucosa biopsy in the pathology department of Beijing Medical University, the detection rate of chronic atrophic gastritis was the highest (60%).