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为了解血清ＡＣＡ水平与冠心病相关性，分别用ＥＬＩＳＡ和免疫比浊法对１４８名健康中老年人的ＡＣＡ－ＩｇＧ、ＩｇＭ、ＩｇＡ和ＴＣ、ＴＧ、ＨＤＬ含量进行了检测。同时测定了３４例住院冠心病人的ＡＣＡ水平。结果表明：在正常组，３类ＡＣＡ均随年龄递增（Ｐ＜０．０１和Ｐ＜０．０５），且男性高于女性（Ｐ＜０．０１和Ｐ＜０．０５），其中ＡＣＡ－ＩｇＧ的消长与血清ＴＧ呈正相关（Ｐ＜０．０５）；冠心病组的ＡＣＡ－ＩｇＧ阳性检出率明显高于正常组（Ｐ＜０．０１）。结果提示血清ＡＣＡ可能通过影响脂代谢参与了冠心病的发生。
To understand the correlation between serum ACA levels and coronary heart disease, the levels of ACA-IgG, IgM, IgA, TC, TG and HDL in 148 healthy middle-aged and elderly people were detected by ELISA and turbidimetry respectively. At the same time, 34 cases of hospitalized coronary heart disease patients with ACA levels. The results showed that in the normal group, the ACA of three types increased with age (P <0.01 and P <0.05), and the male was higher than the female (P <0.01 and P <0.05) The increase and decrease of IgG was positively correlated with serum TG (P <0.05). The positive rate of ACA-IgG in CHD group was significantly higher than that in normal group (P <0.01). The results suggest that serum ACA may be involved in the pathogenesis of coronary heart disease by affecting lipid metabolism.