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乳腺癌骨髓转移很早就可能发生,骨髓微小转移与乳腺癌激素受体表达的相关性研究不多。采用巢式聚合酶链反应(PCR),通过扩增乳腺组织特异性基因乳球蛋白(hMAM)mRNA反映乳腺癌患者骨髓微小转移,探讨乳腺癌骨髓微小转移与激素受
Bone marrow metastasis of breast cancer may occur very early, little correlation between bone marrow micrometastases and breast cancer hormone receptor expression. Nested polymerase chain reaction (PCR) was used to detect bone marrow micrometastases in breast cancer patients by amplifying mRNA of mammary gland tissue-specific gene lactamase (hMAM) mRNA and to explore the relationship between micrometastases and hormone receptors in breast cancer