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目的通过分析不同年龄女性人群心率减速力(DC)的昼夜变化,探讨年龄及昼夜节律对女性DC的影响。方法 339例健康女性按年龄分成4组:18~30岁(青年组),31~44岁(壮年组),45~55岁(围绝经期组),56~70岁(老年组)。各组人群行24 h动态心电图检查,计算机自动测定受捡人群24 h以及白昼(15:00~20:00)和夜间(00:00~05:00)的DC值并进行心率变异性(HRV)分析。结果随着年龄增长,女性24 h DC、HRV及HR均呈降低趋势;各年龄组女性夜间DC以及RMSSD值均显著高于白天;DC与HR以及SDNN、RMSSD密切相关。结论健康女性的DC随着年龄增长而下降,且呈昼夜节律变化;DC与HRV密切相关。
Objective To investigate the effects of age and circadian rhythm on female DC by analyzing the diurnal changes of heart rate deceleration (DC) in different age groups. Methods 339 healthy women were divided into 4 groups by age: 18-30 years old (youth group), 31-44 years old (aged group), 45-55 years old (perimenopausal group), 56-70 years old (elderly group). The 24-hour ambulatory electrocardiogram (ECG) was performed in each group. The DC values of 24 h, daytime (15: 00-20: 00) and nighttime (00: 00-05: 00) were collected and the heart rate variability (HRV )analysis. Results With age, the DC, HRV and HR decreased at 24 h. The values of DC and RMSSD at night in women of all age groups were significantly higher than those of daytime. DC and HR, SDNN and RMSSD were closely related. Conclusion The DC of healthy women decreased with age, and the circadian rhythm was changed. DC was closely related to HRV.