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[目的]探讨诺舒阻抗控制子宫内膜消融术(简称诺舒手术)治疗难治性异常子宫出血(AbnormaLUter-ineBLeeding,AUB)的临床疗效.[方法]选择难治性AUB患者68例,采用诺舒手术治疗,记录患者手术情况、并发症及术后随访情况.[结果]68例手术均顺利完成,诺舒手术治疗时间28~120(61.90±19.73)s;术中出血量均<10mL,术中术后均无严重并发症发生.术后1、3、6、12、24个月有效率分别为100%(68／68)、100%(68／68)、98.53%(67／68)、98.53%(67／68)、97.30%(36／37);闭经率分别为63.23%(43／68)、63.23%(43／68)、63.23%(43／68)、63.23%(43／68)、59.45%(22／37).术后3个月血红蛋白为(103.12±7.74)g／L ,显著高于术前的(92.70± 8.26)g／L,其差异有统计学意义(P<0.05).[结论]诺舒手术治疗难治性AUB安全、有效,尤其适用于保守治疗无效及合并严重内科疾病不能耐受药物及子宫切除术的难治性AUB患者.“,”[Objective]ToexpLorethevaLueofNovaSuerimpedancecontroLLedendometriaLabLationsystemin thetreatmentofrefractoryabnormaLuterinebLeeding (AUB).[Methods]AtotaLof68patientswithrefractory AUBweretreatedwithNovaSureimpedancecontroLLedendometriaLabLation.GeneraLsurgeryprocedure,compLi-cationscurativeeffectandfoLLow-upresuLtswererecorded.[ResuLts]ThesurgerywassuccessfuLLycompLetedin aLL68cases.TheNovaSuretreatmenttimewas28~120 (mean61.90±19.73)s.TheintraoperativebLeedingwas Lessthan10mLwithnoseriouscompLicationsoccurredduringtheoperation.Atpostoperative1month,3months, 6months,12 monthsand24 months,theeffectiveratesofmenstruaLimprovementwere100% (68／68),100% (68／68),98.53%(67／68),98.53%(67／68)and97.30%(36／37),respectiveLy.Theratesofamenorrheawere63. 23%(43／68),63.23%(43／68),63.23%(43／68),63.23%(43／68)and59.45%(22／37),respectiveLy.At3 months afteroperation,thepostoperativehemogLobinwas(103.12±7.74g／L),whichwashigherthanthepreoperative hemogLobin (92.70±8.26g／L).ThedifferencewasstatisticaLLysignificant(P<0.05).[ConcLusion]NovaSureis safeandeffectiveforthetreatmentofAUB.SurgerycanevenbeperformedinanoutpatientcLinic.NovaSureises-peciaLLysuitabLeforrefractoryAUBpatientswithconservativetreatmentfaiLureandseveremedicaLdiseaseswho cannottoLerantdrugsandhysterectomy.