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恶性肿瘤、重症肌无力及带状疱疹都与机体的免疫功能紊乱有关,资料表明恶性肿瘤可合并一些免疫性疾病,但与重症肌无力及带状疱疹同时伴发者少见,现将1例报道如下。患者,男,71岁。因进行性吞咽困难3月于1984年11月28日入院,内镜及病理检查示食管上、中段低分化癌,长约6~7cm,B超检查未见腹腔淋巴结及脏器转移。从1984年12月起经4疗程放射治疗及支持治疗,症状获长时间缓解。1988年初,患者开始出现双眼脸下垂、眼球外展受限、复视等症状,口服吡啶斯的明后症状减轻。1年后上述症状加重,并出现乏力、咀嚼吞咽困难,休息后可好转,于1990年6月12日拟肌无力原因待查再次入院。神经系检查:双睑下垂,眼裂最大时0.5cm,双眼球外展受限,咽反射迟钝,呼吸短促,四肢
Malignancies, myasthenia gravis and shingles are related to the body’s immune dysfunction, the data show that malignant tumors may be associated with some immune diseases, but with myasthenia gravis and concomitant rare, we now report a case as follows. Patient, male, 71 years old. March due to progressive dysphagia admitted to hospital on November 28, 1984, endoscopic and pathological examination showed the upper esophagus, the middle of poorly differentiated cancer, about 6 ~ 7cm, B-ultrasound did not find abdominal lymph node and organ metastasis. From December 1984 onwards after 4 courses of radiotherapy and supportive treatment, the symptoms were prolonged remission. In early 1988, patients began to appear face drooping eyes, eye outreach limited, diplopia and other symptoms, symptoms of oral pyridostigmine alleviate. One year later the above symptoms aggravated, and appeared weak, chewing swallowing difficulties, after the break can be improved, on June 12, 1990 due to myasthenia gravis to be re-admitted to hospital. Nervous system examination: eyelid ptosis, maximum 0.5cm when the eyelid, eye ball outreach limited, slow pharyngeal reflex, shortness of breath, limbs