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饮酒时尿量增加,但尿钠排出量减少,体外实验表明,酒精可使钠从细胞内转移到细胞外,使细胞内钠浓度保持低值的Na-K泵活性增高。在饮酒引起体内钠潴留时,细胞内钠浓度是否降低?然而,在体内酒精引起的变化更为复杂。例如对Na-KATP酶不可缺少的镁离子,饮酒时经尿大量排出。作者测定饮酒时红细胞内钠离子浓度(同不饮酒时相比):饮酒前和饮酒后2小时均无显著差异(8.38±0.745对8.47±0.692mmol/L,RBC;8.58±0.690对8.58±0.792mmol/L,RBC);饮酒后4小时和6小时较高(8.91±0.641对8.48±0.707)mmol/L,RBC,P<0.05;8.87±0.627对8.50±0.571mmol/L,BBC,P<0.01)。鉴于大量饮酒的长期影响,
Urine increased while drinking, but reduced urinary sodium excretion, in vitro experiments show that alcohol can transfer sodium from the cell to the outside of the cell, leaving the sodium concentration in the cell to maintain low Na-K pump activity increased. Does sodium intracellular concentration decrease when drinking causes sodium retention in the body? However, alcohol-induced changes in the body are more complicated. For example, Na-KATP enzyme indispensable magnesium ions, drinking large quantities of urine excretion. The authors determined that there was no significant difference in sodium intracellular erythrocyte concentrations (as compared to non-alcohol consumption) during alcohol consumption: no significant difference was observed between pre-alcohol intake and 2 hours after drinking (8.38 ± 0.745 vs. 8.47 ± 0.692 mmol / L, RBC; 8.58 ± 0.690 vs. 8.58 ± 0.792 (RBC, P <0.05); 8.87 ± 0.627 vs 8.50 ± 0.571 mmol / L, BBC, P < 0.01). Given the long-term impact of heavy drinking,