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目的观察米索前列醇与缩宫素联合应用预防剖宫产产后出血的临床效果。方法将沧州市妇幼保健院2010年1月至2010年12月剖宫产的200例产妇随机分为观察组和对照组,对照组100例产妇术后给予宫缩素预防产后出血,观察组100例产妇给予米索前列醇与缩宫素联合应用预防产后出血。结果观察组产后出血率为5.0%,对照组产后出血率为21.0%,两组数据比较统计学有意义(P<0.05);观察组产妇产后2h与产后24h的出血量分别为(102.4±22.2)ml、(137.8±28.8)ml;对照组分别为(226.8±25.5)ml、(562.4±32.6)ml,两组数据比较统计学有意义(P<0.05)。结论剖宫产孕妇术后给予米索前列醇与缩宫素联合治疗能够有效的降低产后出血,值得临床中应用。
Objective To observe the clinical effect of misoprostol combined with oxytocin in preventing bleeding after cesarean section. Methods 200 maternal women of Cesarean section from January 2010 to December 2010 in Cangzhou were randomly divided into observation group and control group. 100 maternal women in control group were treated with oroctopsy to prevent postpartum hemorrhage. The observation group 100 Cases of maternal administration of misoprostol combined with oxytocin to prevent postpartum hemorrhage. Results The postpartum hemorrhage rate in the observation group was 5.0% and the postpartum hemorrhage rate in the control group was 21.0%. The data of the two groups were statistically significant (P <0.05). The bleeding volume in the observation group at 2 h postpartum and at 24 h postpartum were (102.4 ± 22.2) ) and (137.8 ± 28.8) ml respectively; the control group were (226.8 ± 25.5) ml and (562.4 ± 32.6) ml, respectively. The data of two groups were statistically significant (P <0.05). Conclusion Cesarean section postoperative pregnant women given misoprostol and oxytocin combined treatment can effectively reduce the postpartum hemorrhage, it is worth the clinical application.