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目的 探讨检测患者血清特异 Ig G4诊断包虫病的效果。 方法 采用两种抗原 (棘球蚴囊液粗抗原及其抗原B)通过 EL ISA法检测棘球蚴病病人、非棘球蚴病病人和健康对照血清特异 Ig G4。 结果 粗抗原和抗原 B检测棘球蚴患者血清特异 Ig G4的阳性率分别为 94.4%和 89.8% ;与部分猪囊尾蚴病患者血清出现交叉反应外 ,与肺吸虫病、旋毛虫病、血吸虫病、肝囊肿等患者的血清以及健康对照血清均未出现交叉反应。 结论 检测棘球蚴患者血清特异 Ig G4敏感性高 ,特异性强 ,具有较好的诊断价值。
Objective To investigate the effect of detecting serum specific Ig G4 in diagnosis of hydatid disease. Methods Serum specific Ig G4 of patients with hydatid disease, non-hydatid cysts and healthy controls were detected by EL ISA using two antigens (echinococcosis crude antigen and antigen B). Results The positive rates of serum specific Ig G4 in echinococcus granulosus with crude antigen and antigen B were 94.4% and 89.8%, respectively. In addition to the cross-reaction with serum of some patients with cysticercosis, , Liver cysts and other serum and healthy control serum did not appear cross-reaction. Conclusion The detection of serum specific Ig G4 in patients with hydatid cyst is highly sensitive and specific and has a good diagnostic value.