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美国耶鲁大学的Thomas Steitz教授等利用X-射线照射核糖体晶体后,产生的愆射图象去获取其分子的至今为止最精确的三维图型。核糖体晶体是细胞内蛋白质的制造工厂。此项研究发表于8月10日版的《科学》杂志上。该研究小组已获得了核糖体最重要部分的分子结构,显示其大小为240亿分之一的细节。这个图像支持了核糖体的一个组成部分RNA的最重要的自我复制分子之一,组成核糖体的RNA和蛋白质二者形成复杂的结构,它能“读取”细胞内复制的遗传密码,并将这些信息转变成有利用价值的分子。研究者已经绘制出核糖体中能催化化学原材料间聚合反应的一部分。该结构能使我们进一步认识到核糖体在早期就可能已经进化,作为一个生产短链蛋白的“机器”。
Professor Thomas Steitz from Yale University in the United States utilized the X-ray irradiation of ribosome crystal to produce the most accurate three-dimensional pattern of its molecules. Ribosomal crystals are the manufacturing plant for intracellular proteins. The study was published in the August 10 issue of Science. The team has obtained the molecular structure of the most important part of the ribosome, showing details at 24 billionths of its size. This image supports one of the most important self-replicating molecules of RNA, a component of the ribosome, which forms a complex structure of both the RNA and the protein that make up the ribosome, which “reads” the intracellular copy of the genetic code and These messages translate into valuable use numerators. Researchers have mapped out some of the ribosomes that catalyze the polymerization between chemical raw materials. This structure enables us to further recognize that ribosomes may have evolved at an early stage as a “machine” for the production of short-chain proteins.