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人乳头瘤病毒(HPV)和包括肛门生殖器部位恶性肿瘤在内的许多皮肤肿瘤有关。在免疫功能受到抑制的患者中更易发生HPV相关的肿瘤。在皮肤疣中出现的空泡化细胞已知是由HPV所致。作者采用聚合酶链反应(PCR)研究了组织病理上有空泡化细胞表现的生殖器外鲍温病患者的皮损,以了解是否有HPV感染。
Human papillomavirus (HPV) is associated with many cutaneous tumors, including those at the anogenital site. HPV-associated tumors are more likely to occur in patients with suppressed immune function. The occurrence of vacuolar cells in cutaneous warts is known to be caused by HPV. The authors used polymerase chain reaction (PCR) to study histopathology with vacuolar cells in patients with genital Bowring Bowel disease lesions to understand whether there is HPV infection.