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选用40只Wistar雄性初断乳大鼠,按体重随机分为本底组、实验组(CCMⅠ组、CCMⅡ组)和正对照组(CaCO3Ⅰ组、CaCO3Ⅱ组)。本底组在实验开始前处死,其它各组均饲以按AOAC配方配制的纯合成饲料,仅其中的钙分别来自Ca-CO3和CCM。CaCO3Ⅰ组和CCMⅠ组的饲料含钙200mg/100g,CaCO3Ⅱ组和CCMⅡ组的饲料含钙400mg/100g,分别达到大鼠推荐量的50%和100%。喂养观察28天。结果表明,CCM组大鼠钙吸收利用率和存留率均极显著高于同一剂量的碳酸钙组。提示CCM作为补钙制剂,较高的生物活性,能够有效地补充钙质,尤其对儿童和老年人,较目前国内外钙剂市场上广泛应用的碳酸钙性能更为优越
Forty Wistar male weanling rats were randomly divided into basal group, experimental group (CCMⅠgroup, CCMⅡgroup) and positive control group (CaCO3Ⅰgroup, CaCO3Ⅱgroup) according to body weight. The background group was sacrificed before the start of the experiment, and the other groups were fed the purely synthetic feed formulated according to the AOAC formula, with only calcium from Ca-CO3 and CCM, respectively. The diet containing 200mg / 100g of calcium and the diet containing 400mg / 100g of CaCO3Ⅱ and CCMⅡwere 50% and 100% of the recommended amount in rats respectively. Feeding observation for 28 days. The results showed that the calcium absorption and retention rate of CCM group rats were significantly higher than the same dose of calcium carbonate group. It is suggested that CCM, as a calcium supplement, has high biological activity and can effectively supplement calcium, especially for children and the elderly, and is superior to the calcium carbonate widely used in the calcium market both at home and abroad