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对抗高血压因子（AHF）的分布特点、不同种属来源的AHF降压效应和舒血管作用以及其是否为已知的血管活性物质等进行观察。结果表明，不论是人还是其他哺乳动物（如大鼠、免、狗等）的红细胞中均存在AHF。在剂量相同的情况下、AHF对大鼠的降压作用以及对大鼠主动脉的舒张作用五种属差异。随着AFH剂量的增加，其降压作用均呈明显的剂量依赖关系。不同剂量组间降压作用具有明显差异（P＜0．05或P＜0.01）。所观察的大鼠各种组织（如脑、心、肾、肝和红细胞等），以红细胞AHF的降压活性最高。多种已知的血管活性物质的特异受体拮抗剂只能阻断其相应的血管活性物质对血压的作用，对AHF的降压活性无影响。
The distribution of antihypertensive agents (AHF), AHF antihypertensive effect and vasodilator effect from different species, and whether they are known vasoactive substances were observed. The results show that AHF is present in both human and other red blood cells in other mammals (eg rats, boobs, dogs, etc.). At the same dosage, the AHF on the antihypertensive effect of rats and the aortic relaxation of rats in five different genus. With the increase of AFH dose, its antihypertensive effect showed a significant dose-dependent. The antihypertensive effects of different dose groups were significantly different (P <0.05 or P <0.01). The observed rat tissue (such as brain, heart, kidney, liver and red blood cells, etc.), the highest antihypertensive activity of erythrocyte AHF. A variety of known specific antagonists of vasoactive substances can only block the corresponding vasoactive substances on blood pressure, the antihypertensive activity of AHF no effect.