卡托普利的不良反应

• 作 者: 陈方倩
• 机 构: 哈尔滨市第一医院 150010
• 出 处: 哈尔滨医药
• 发表日期: 1999年03期
• 关键词: 不良反应 充血性心力衰竭 粒细胞缺乏症 味觉障碍 降压作用 心脏功能 临床用途 组织系统 平均血压 血管紧张素

卡托普利(Captopril CPT)是第一个口服有效的血管紧张素转化酶抑制剂,问世虽然只有十余年,但该药已广泛应用于高血压及充血性心力衰竭(CHF)的治疗,对多种类型高血压均有明显降压作用,并能改善充血性心力衰竭患者的心脏功能,并取得肯定疗效。随着临床用途的日益扩大,各种不良反应报道也日渐增多,主要有皮疹、瘙痒、味觉障碍、蛋白尿、粒细胞缺乏症及其他组织系统等的不良反应,在此将近年来有关卡托普利的不良反应总结整理如下,以供同行参考。

Captopril CPT is the first orally available angiotensin-converting enzyme inhibitor that has been available for more than 10 years but is widely used in the treatment of hypertension and congestive heart failure (CHF) On many types of hypertension have significant antihypertensive effect, and can improve cardiac function in patients with congestive heart failure, and achieved a positive effect. With the increasing clinical use, a variety of adverse reactions are reported increasing, there are rash, itching, taste disorders, proteinuria, agranulocytosis and other tissue systems and other adverse reactions, in this will be related to the recent Captop Lee’s adverse reactions summarized as follows, for peer reference.