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目的:了解机器人辅助下前列腺癌根治术（RALP）术后发生肾损伤（AKI）的危险因素。方法:回顾性分析2017年6月至2019年6月南京大学附属鼓楼医院605例RALP患者临床资料，采用Logistic回归法分析影响术后AKI的影响因素。结果:单因素分析显示：年龄（n P=0.001）、贫血（n P=0.036）、低蛋白血症（n P=0.001）、冠心病（n P=0.040）、高血压（n P=0.042）、服用血管紧张素转化酶抑制剂（ACEI）/血管紧张素Ⅱ受体拮抗剂（ARB）类降压药（n P=0.025）、术中平均动脉压（MAP）<55 mmHg（1 mmHg=0.133 kPa）的时间（n P=0.000）差异均有统计学意义（n P<0.05）；多因素Logistic回归分析示年龄（n P=0.016）、低蛋白血症（n P=0.009）、MAP<55 mmHg的时间（n P=0.003）差异均有统计学意义（n P<0.05）。n 结论:年龄、贫血、低蛋白血症、冠心病、高血压、服用ACEI/ARB类降压药、MAP<55 mmHg的时间均是术后患者发生AKI的危险因素；其中年龄、低蛋白血症、MAP<55 mmHg的时间是术后发生AKI的独立危险因素。临床上可以根据上述危险因素采取相应的预防措施，保护肾脏功能，降低围手术期病死率。“,”Objective:To explore the risk factors of acute kidney injury (AKI) after robot-assisted radical prostatectomy.Methods:The clinical data of 605 patients who underwent robot-assisted radical prostatectomy in Nanjing Drum Tower Hospital from June 2017 to June 2019 were retrospectively analyzed. The independent risk factors of AKI were analyzed by Logistic regression.Results:Univariate analysis showed that age (n P = 0.001), anemia (n P = 0.036), hypoalbuminemia (n P = 0.001), coronary heart disease (n P = 0.040), hypertension (n P = 0.042), use of ACEI/ARB drugs (n P = 0.025), duration of MAP < 55 mmHg (1 mmHg = 0.133 kPa)( n P = 0.000) presented statistical significance(n P < 0.05). Multivariate Logistic regression analysis showed that there were significant difference in age ( n P = 0.016), hypoalbuminemia (n P = 0.009), duration of MAP < 55 mmHg ( n P = 0.003).n Conclusions:Age, anemia, hypoalbuminemia, coronary artery disease, hypertension, use of ACEI/ARB drugs, duration of MAP < 55 mmHg are risk factors of postoperative AKI, among which age, hypoalbuminemia, duration of MAP < 55 mmHg are independent risk factors.