不同延期神经再支配环杓后肌方法的疗效观察

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目的:探讨环杓后肌延期神经再支配的方法及时机。方法:将29只狗分成三组,两个实验组在喉返神经切断后即刻、4、6、8、10、12个月分别将膈神经与喉返神经吻合选择性支配环杓后肌和颈袢神经—胸骨甲状肌蒂植入环杓后肌,对照组喉返神经切断后各时间不作任何手术。结果:两个实验组6个月后行喉镜、神经肌电及肌收缩力、组织化学证实:神经吻合组各时间效果明显好于神经肌蒂植入组,但两种术式疗效均随病程延长而下降。结论:神经吻合法延期神经再支配环杓后肌6个月内效果较好,而神经肌蒂植入法治疗环杓后肌麻痹最好不晚于失神经后4个月,否则效果不佳 Objective: To investigate the method and timing of delaminated coccyx muscle denervation. Methods: Twenty-nine dogs were divided into three groups. The two experimental groups were treated with phrenic nerve and recurrent laryngeal nerve anastomosis selectively and directly after posterior recurrent laryngeal nerve at 4, 6, 8, 10 and 12 months Cervical nerve - sternothyroid muscle pedicle descending cricothyral muscle, control group, recurrent laryngeal nerve after each time without any surgery. Results: The laryngoscope, neuromuscular and muscle contractility were observed in the two experimental groups after 6 months. Histochemistry confirmed that the nerve anastomosis group was significantly better than the neuromuscular grafting group at each time, but the efficacy of the two kinds of operation were Prolonged and decreased duration. CONCLUSION: Nerve anastomosis is effective in delaying circumflex crescent muscle within 6 months, and neuromuscular placement is the best way to treat posterior ciclipopalgia paralysis no later than 4 months after denervation, otherwise the effect is not good
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