Synthesis and Structure of 5-Amino-6-(4-fluorophenylamino)-3-methylthio-1-phenyl-1H-pyrazolo[3,4-d]p

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The title compound (C18H15FN6OS) has been synthesized and its crystal structure was determined by X-ray analysis. The crystal belongs to monoclinic system, space group P21/n with a = 13.983(10), b = 7.337(5), c = 16.702(12) , α = 90, β = 98.277(12), γ = 90o, V = 1696(2) 3, Z = 4, Dc = 1.498 g/cm3, Mr = 382.42, μ = 0.224 mm-1, F(000) = 792, the final R = 0.0362 and wR = 0.0878 for 2579 observed reflections with I > 2((I). In the title compound, the atoms of C(1), C(2), C(3), C(4), C(5), N(1), N(2), N(3), N(4), N(5), N(6), O(1) and S(1) form a fully delocalized system with the average deviation of 0.0307 . There exists a part of electron delocalization over the planes of I (pyrazolo[3,4-d]pyrimidin-4-one moiety), II (phenyl moiety) and III (p-fluo- rophenylamine moiety). In the molecule, intermolecular hydrogen bonds between N(6)-H(6)…O(1) and C(15)-H(15)…O(1) are observed. The crystal compound to C monoclinic system, space group P21 / n with a = 13.983 (10), b = 7.337 (5), c = 16.702, α = 90, β = 98.277 (12), γ = 90o, V = 1696 23, Z = 4, Dc = 1.498 g / cm3, Mr = 382.42, μ = 0.224 mm- 1, F (000) = 792, the final R = 0.0362 and wR = 0.0878 for 2579 at refs with I> 2 (I). (3) C (4) C (5) N (1) N (2) N (3) N 4 N 5 N 6 O 1 and S (1) form a fully delocalized system with the average deviation of 0.0307 There. There exists a part of electron delocalization over the planes of I (pyrazolo [3,4- d] pyrimidin-4-one moiety), II (phenyl moiety) In the molecule, intermolecular hydrogen bonds between N (6) -H (6) ... O (1) and C (15) -H (15) ... O .
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