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目的 进一步了解小儿病毒性脑炎及脑膜炎急性期或亚急性期脑脊液细胞学 (CSFC)变化及临床意义。方法 取患儿脑脊液 (CSF)应用微型脑脊液细胞玻片离心法收集细胞 ,MGG染色 ,光镜检查。结果 6 0 % (33/ 5 5 )CSF常规白细胞计数有增高 ,而 CSFC异常为 78.2 % (43/ 5 5 ) ,其中以淋巴细胞为主的混合性细胞反应占 5 1.2 % (2 2 /4 3) ,以淋巴细胞为主的免疫活性细胞反应占 39.5 % (17/ 4 3) ,以嗜中性粒细胞为主的混合性细胞反应占 7.0 % (3/4 3)。结论 CSFC检查阳性率高 ,且便捷 ,对病毒性脑炎的早期诊断有重要的参考价值。
Objective To further understand the changes of viral encephalitis and meningitis in acute or subacute cerebrospinal fluid cytology (CSFC) and its clinical significance. Methods Children with cerebrospinal fluid (CSF) were collected by using microcentrifugal cytoskeleton centrifugation, MGG staining and light microscopy. Results The counts of routine white blood cells (CSF) were increased in 60% (33/55) of the patients, while the abnormality of CSFC was 78.2% (43/55). Among them, mixed lymphocyte reaction accounted for 52.2% 3), 39.5% (17/43) were lymphocyte-predominant immunocompetent cells and 7.0% (3/4 3) were neutrophil-based mixed-cell reactions. Conclusion The positive rate of CSFC examination is high and convenient. It has important reference value for the early diagnosis of viral encephalitis.