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ＬＰ（ａ）与ＮＩＤＤＭ心血管并发症关系的探讨山西医学院第二附属医院（０３０００１）李兴，许笑梅，左芮文太原市商业职工医院张晓慧太原市中心医院田巧兰本文测定了５８例ＮＩＤＤＭ患者的血脂及ＬＰ（ａ）水平，旨在分析探讨ＮＩＤＤＭ患者血脂及ＬＰ（ａ）与心血管并发症的关系。资料和方法—、对象；ＮＩＤＤＭ组：根据１９８５年ＷＨＯ糖尿病诊断标准确诊为ＮＩＤＤＭ患者５８例，男２８例，女３０例，平均年龄５２．３１±１０．２５岁。平均空腹血糖８．９１±１．２１ｍｍｏｌ／Ｌ。其中有心血管并发症者３３例（冠心病１８例，高血压８例，糖尿病性肾病７例）。对照组：从健康体检人中选择无冠心病、高血压病、糖尿病、肝肾疾病、内分泌疾病及高脂血症者４２人，男２２人，女２０人，平均年龄５２．２３±１２．７４岁。均无上述疾病的家族史。二、方法：血标本为早晨空腹血。酶法测定血清胆固醇（ＴＣ）、甘油三酯（ＴＧ）、高密度脂蛋白胆固醇（ＨＤＬ—Ｃ）；用磷钨酸—镁沉淀、酶法测定胆固醇；免疫透射比浊法测定ａｐＯＡ１、ａｐｏＢ１００；ＥＬＬＳＡ法测定ＬＰ（ａ）。均由生化教研室血脂专题研究组测定。结果—、血脂：ＮＩＤＤＭ组ＴＧ、ＴＣ（１．９０±１．２２、５．６９±
Relationship between LP (a) and NIDDM Cardiovascular Complications The Second Affiliated Hospital of Shanxi Medical University (030001) Li Xing, Xu Xiaomei, Zu Ruiwen Taiyuan City Commercial Workers Hospital Zhang Xiaohui Taiyuan Central Hospital Tian Qiaolan This article measured 58 cases of NIDDM patients The levels of lipids and LP (a) were analyzed to explore the relationship between lipid and LP (a) and cardiovascular complications in patients with NIDDM. Materials and Methods-, Subjects; NIDDM group: According to the WHO diagnostic criteria of WHO in 1985, 58 cases were diagnosed as NIDDM patients, including 28 males and 30 females, with an average age of 52.31 ± 10.25 years. The average fasting glucose 8.91 ± 1.21mmol / L. There are 33 cases of cardiovascular complications (coronary heart disease in 18 cases, hypertension in 8 cases, 7 cases of diabetic nephropathy). In the control group, 42 non-CHD, hypertension, diabetes, liver and kidney disease, endocrine disease and hyperlipidemia were selected from the healthy people. There were 22 males and 20 females with an average age of 52.23 ± 12. 74 years old. No family history of the above diseases. Second, methods: blood samples for fasting blood in the morning. Enzymatic determination of serum cholesterol (TC), triglyceride (TG) and high density lipoprotein cholesterol (HDL-C); determination of cholesterol by phosphotungstic acid-magnesium precipitation and enzymatic method; determination of apOA1 and apoB100 by immunoturbidimetry; ELLSA method for the determination of LP (a). By the Department of Biochemistry, Department of lipid research team determined. Results -, Lipid: NIDDM group TG, TC (1.90 ± 1.22,5.69 ±