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脂质体(Liposome)是一种人工合成的脂质膜性小球,1965年由Bangham等首先描述.其结构类同生物膜,作为生物膜的研究模型,使得生物膜的许多特性得以了解.近年来,它作为载体微球,在医学研究中应用广泛,不仅可作为溶质分子,如酶、药物、离子等的载体,使其有选择地作用于靶器官,集中发挥更有效的作用;而且还可作为抗原载体,增强机体免疫应答,发挥佐剂作用.此外,它还可用于提高体外抗原-抗体反应的敏感性和可检测性.因此,它在免疫学中的应用,已受到学者们越来越多的重视.本文将对脂质体的制备方法及其
Liposomes are synthetic, lipid-based, lipid-based microspheres first described by Bangham et al. In 1965. Their structural analogues with biofilms, as a model for biofilm research, have led to the understanding of many of the properties of biofilms. In recent years, it has been widely used in medical research as a carrier microsphere. It can not only act as a carrier of solute molecules such as enzymes, drugs and ions, but also selectively act on target organs and concentrate more effectively. Moreover, But also as an antigen carrier to enhance the body’s immune response and play an adjuvant role.In addition, it can also be used to improve the sensitivity and detectability of antigen-antibody reaction in vitro.Therefore, its application in immunology has been scholars More and more attention.This article will be liposome preparation method and its