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A curcumin derivative ligand,1,7-bis(3-methoxyl-4-acetoxyl)phenyl-1,6-heptadiene-3,5-diketone (diacetylcurcumin,abbreviated as HL),and its Cu and Ni complexes have been synthesized and fully characterized by elemental analyses,IR,1 HNMR and molar conductivity.The resulting complexes exhibit two-photon excited fluorescence (TPEF) in DMF,and have been proven to be potentially useful for two-photon microscopy imaging in living cells.In addition,cytotoxicity tests showed that the low-micromolar concentrations of ML 2 did not cause significant reduction in cell viability over a period of at least 24 h and should be safe for further biological studies.
A curcumin derivative ligand, 1,7-bis (3-methoxyl-4-acetoxyl) phenyl-1,6-heptadiene-3,5-diketone (diacetylcurcumin, abbreviated as HL), and its Cu and Ni complexes have been synthesized and fully characterized by elemental analyzes, IR, 1 HNMR and molar conductivity. The resulting complexes exhibit two-photon excited fluorescence (TPEF) in DMF, and have been proven to be potentially useful for two-photon microscopy imaging in living cells. In addition, cytotoxicity tests showed that the low-micromolar concentrations of ML 2 did not cause significant reduction in cell viability over a period of at least 24 h and should be safe for further biological studies.