论文部分内容阅读
已知以脉冲式给予促性腺激素释放激素(GnRH)可刺激垂体前叶释放促性腺激素。已有不少报导对原发性或继发性闭经妇女以脉冲式 GnRH治疗后诱导排卵及妊娠成功。本文旨在建立选择病例的标准。12例不同情况卵巢功能紊乱妇女以缓慢脉冲式GnRH 治疗。所有病例催乳素水平正常(<25ng/ml),年龄22～41岁。按平均 LH 及 FSH 基值不同分为2组,第1组8例,LH 2.3±1.5 mIU/ml,FSH2.5±1.2mIU/ml,表现为原发性闭经及月经稀发。共治疗21个 GnRH 周期,其中16次静脉,5次皮下给药。21周期中19次 GnRH 脉冲
It is known that pulsatile administration of gonadotropin-releasing hormone (GnRH) stimulates gonadotropin release from the anterior pituitary. Many reports have reported successful induction of ovulation and pregnancy after pulsed GnRH treatment of primary or secondary amenorrhea women. This article aims to establish the criteria for selecting cases. Twelve different cases of ovarian dysfunction women with slow pulse GnRH treatment. All cases of normal prolactin levels (<25ng / ml), aged 22 to 41 years old. According to the average value of LH and FSH, the patients were divided into two groups. The first group included 8 cases, LH 2.3 ± 1.5 mIU / ml and FSH 2.5 ± 1.2 mIU / ml, which manifested as primary amenorrhea and oligomenorrhea. A total of 21 GnRH cycles were treated, with 16 intravenous and 5 subcutaneous doses. 19 GnRH pulses in 21 cycles