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妊娠相关血浆蛋白 A(PAPP-A)属于近年来在人胎盘测到的一组妊娠蛋白,它是一种分子量为750000道尔顿和有α_2电泳移动性的糖蛋白,随妊娠进展孕妇血清 PAPP-A 浓度也增加,并且认为胎盘是产生 PAPP-A 的部位。近年来报告提示,在未孕妇女血清和人精液内 PAPP-A 有容易测到的数量。本文报导的是对体外受精(IVF)妇女,过度刺激的排卵前囊状卵泡内 PAPP-A 样免疫反应性的检测。29名不孕妇女用枸橼黢克罗米芬,人绝经促性
Pregnancy-associated plasma protein A (PAPP-A) belongs to a group of pregnancy proteins measured in human placenta in recent years. It is a glycoprotein with a molecular weight of 750,000 Daltons and α 2 electrophoretic mobility. Pregnancy-related serum PAPP The -A concentration also increased, and the placenta was considered to be the site where PAPP-A was produced. Recent reports suggest that PAPP-A is readily detectable in serum and human semen from women who are not pregnant. This paper reports the detection of PAPP-A-like immunoreactivity in overactive ovarian sac follicles in women with in vitro fertilization (IVF). 29 infertile women with black citron clomiphene, menopause