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自身免疫甲状腺病（ＡＩＴＤ）甲状腺滤泡上皮细胞和浸润的淋巴细胞均可表达细胞因子基因及产生相应细胞因子，其产生类型可能以辅助Ｔ细胞１（ＴＨ１）占优势。这些因子作为免疫介质和内分泌介质参与其发病。ＡＩＴＤ可能是ＴＨ１细胞介导的自身免疫性疾病，可通过矫正ＴＨ１和ＴＨ２类细胞因子的失衡来预防或治疗ＡＩＴＤ。
Autoimmune thyroid disease (AITD) Both thyroid follicular epithelial cells and infiltrating lymphocytes can express cytokine genes and produce corresponding cytokines, and the type of their production may predominate with helper T cell 1 (TH1). These factors as immune and endocrine mediators involved in its pathogenesis. AITD may be a TH1 cell-mediated autoimmune disease that prevents or treats AITD by correcting the imbalance of TH1 and TH2 cytokines.