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目的:了解孕妇生殖道B群链球菌(GBS)携带情况及对新生儿的影响。方法:对1 019例产妇产前取阴道下1/3处分泌物,分娩后取新生儿咽、耳分泌物及脐带血分别检测GBS,并观察母婴情况。结果:产前母体GBS(+)104例,分离率10.21%,新生儿GBS(+)47例,分离率45.19%。GBS阳性孕妇既往流产史、胎膜早破、早产及产褥感染发生率较阴性者高(P<0.05),产时新生儿低体重、新生儿肺炎、胎膜早破、新生儿窘迫发生率均比阴性者高,差异具有统计学意义(P<0.05)。产后体温及白细胞无明显升高,两组无差异(P>0.05)。结论:为降低GBS感染对围产期母儿的影响,产前应对孕妇进行常规GBS筛检,阳性孕妇应给予预防性治疗并于产前复查,产时对GBS阳性孕妇及新生儿给予适当治疗以避免发生并发症。
OBJECTIVE: To understand the carriage of Streptococcus group B Streptococcus (GBS) in pregnant women and the impact on neonates. Methods: 1 019 maternal prenatal vaginal discharge to take the next third place secretions, after delivery of neonatal pharynx, ear secretions and cord blood were detected GBS, and observed the situation of maternal and child. Results: Prenatal maternal GBS (+) 104 cases, the isolation rate of 10.21%, 47 cases of neonatal GBS (+), the isolation rate of 45.19%. The incidence of previous miscarriage, premature rupture of membranes, premature delivery and puerperal infection in GBS positive pregnant women was significantly higher than that in negative pregnant women (P <0.05). Low birth weight, neonatal pneumonia, premature rupture of membranes, and neonatal distress rate Higher than the negative, the difference was statistically significant (P <0.05). Postpartum body temperature and no significant increase in leukocytes, no difference between the two groups (P> 0.05). Conclusion: In order to reduce the impact of GBS infection on perinatal maternal, prenatal treatment of pregnant women should be routinely GBS screening, positive pregnant women should be given prophylactic treatment and prenatal review, during delivery of GBS-positive pregnant women and newborns given appropriate treatment To avoid complications.