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目的观察地塞米松(DXM)对降低脑出血患者颅内压(ICP)的效果。方法 182例高血压脑实质内出血术后患者,随机分为局部使用DXM组(A组,40例)、激素冲击组(B组,43例)、常规使用激素组(C组,52例)、对照组(D组,47例),观察四组患者术后不同时刻的ICP值,并进行比较。结果排除影响ICP监测准确性因素及并发症(二次出血、引流管堵塞、呼吸道阻塞、尿管阻塞、躁动及排便困难等),四组术后7 d内ICP水平组间比较差异无统计学意义(P>0.05)。结论使用地塞米松对高血压脑实质内出血术后患者7 d内ICP无影响。
Objective To observe the effect of dexamethasone (DXM) on reducing intracranial pressure (ICP) in patients with intracerebral hemorrhage. Methods A total of 182 hypertensive intraparenchymal hemorrhage patients were randomly divided into four groups: DXM group (40 cases), hormonal shock group (43 cases), hormone group (C group, 52 cases) Control group (D group, 47 cases), the four groups were observed at different time after the ICP value and compared. The results exclude the accuracy of ICP monitoring factors and complications (secondary bleeding, drainage tube blockage, airway obstruction, catheter obstruction, agitation and defecation difficulties, etc.) within 7 days after the ICP level between the four groups no significant difference Significance (P> 0.05). Conclusion Dexamethasone has no effect on ICP within 7 days after hypertensive intraparenchymal hemorrhage.